A scientific seminar dedicated to the "Year of Heydar Aliyev" was held at the Institute of Biophysics of the Ministry of Science and Education of Azerbaijan on the topic "Molecular docking study of the interaction of cationic anti-cancer Glu-Gln-Arg-Pro-Arg peptide with various proteins and its effect mechanism on lipid monolayers."

The seminar was opened by the Director of the Institute, Corresponding Member of the Azerbaijan National Academy of Sciences Oktay Gasanov. He emphasized that in this significant year for our country, along with the 100th anniversary of the birth of the National Leader Heydar Aliyev, events are being held nationwide to celebrate the 100th anniversary of his wife, the prominent ophthalmologist, academician Zarifa Aliyeva. He also mentioned that in connection with this important year, further scientific seminars will be held at the Institute.

The next speaker was Matanat Baxishova, Chair of the Young Scientists and Specialists Council and a scientific researcher at the Molecular and Cell Biochemistry Laboratory. In her presentation, she explained that the cationic pentapeptide Glu-Gln-Arg-Pro-Arg (EQRPR) belongs to a family of anti-cancer peptides with significant anti-cancer activity. Initially, the mechanism of this activity was unknown, but after scientific research conducted in the laboratory, the pharmaceutical profile of the peptide was examined, and its anti-cancer properties were identified through in silico molecular docking studies. M. Baxishova also added that the effect of EQRPR on the DPPC (dipalmitoylphosphatidylcholine) monolayer was studied using the Langmuir monolayer technique, and the results were discussed in terms of interactions. To evaluate the binding mechanisms, the binding of the pentapeptide and its various amino acid-substituted analogs to both the epidermal growth factor receptor (EGFR tyrosine kinase) and proto-oncogene tyrosine protein kinase (FYN) was investigated. The significant results of the research were published in the journal "Biomolecular Structure and Dynamics" with an impact factor of 5.235.

At the end of the presentation, a session of questions and answers was held, and discussions took place.

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